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The other reason why you may be prescribed HCG while on testosterone supplementation is to prevent the testes from stopping natural testosterone production. You see, when the brain notices an increase in testosterone levels in the bloodstream, it does not have the stimulus needed to support further testosterone production. The hypothalamus releases a hormone called GnRH – gonadotropin- releasing hormone that goes to the pituitary gland to signal the secretion of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). LH is the hormone that stimulates the Leydig cells in the testes to produce testosterone. This stimulus decreases in men receiving testosterone replacement.