Women can take testosterone as a cream, through a patch or in the form of pellet implants, which have the highest consistency of delivery. Synthesized from yams or soybeans, and compounded of pure, bioidentical testosterone, the pellets, each slightly larger than a grain of rice, are inserted just beneath the skin in the hip in a one-minute outpatient procedure. They dissolve slowly over three to four months, releasing small amounts of testosterone into the blood stream, but speeding up when needed by the body -- during strenuous activities, for example -- and slowing down during quiet times, a feature no other form of hormone therapy can provide.
This is a common problem with pellets. If you go looking for forums on the matter, you will see that it is rather typical for patients to have a similar response somewhere around the 4th and 5th implantation. This stems from poor oversight/management, and design flaws in the pellets themselves. Keep in mind that all pellets are made the same way. This may seem beneficial at first glance, however, what this really means is that “6 months” worth of medication dissolves in a way that sends your levels far too high in the first month, and then plummeting far too fast and low in the next 2-3.
Hi Caroline. Professor Studd is quite unusual in prescribing Utrogestan for such a short period as this can be more risky in terms of thickened endometrial lining. I think he does this so that women can avoid the symptoms of progesterone intolerance. The standard recommendation is that progesterone be taken for 12-14 days a month. This is to ensure that you have a proper bleed and all the endometrial lining is shed. If you take Utrogestan for only 7 days a month you will need to be closely monitored for thickening of your endometrial lining by having more frequent vaginal ultrasounds. Professor Studd usually advises women to start taking Utrogestan on the 1st day of the calendar month as this is the simplest procedure, so you could try that. You could try and work out your cycle based on the date of your last period or if you have already started taking the EstroGel, opt for any day. If you haven’t already started, start the EstroGel and count day one of EstroGel as day one of your cycle and then start the Utrogestan on day 12. I hope that helps.